HIV Prevention Injection Finally Unveiled In Africa

By Akinwale Kasali

The groundbreaking new Human Immune Virus, HIV, Prevention Injection has been unveiled in South Africa, Eswatini and Zambia. It was unveiled on Monday, December 1, 2025.

This is the first public rollout of the drugs, as the aforementioned countries have the World’s Highest HIV Burden.

The drug known as Lenacapavir, is taken twice a year, and has been shown to reduce the risk of HIV transmission by more than 99.9 percent, making it functionally akin to a powerful vaccine.

It was gathered that in South Africa, where one in five adults lives with HIV, a Wits University Research Unit oversaw the rollout as part of an initiative funded by Unitaid, the United Nations health agency.

“The first individuals have begun using lenacapavir for HIV prevention in South Africa … making it among the first real-world use of the 6-monthly injectable in low-and middle-income countries,” Unitaid said in a statement.

Though the research did not specify how many people received the first doses of the drug, which cost $28,000 per person a year in the United States.

A broader national rollout is said to be expected next year.

Neighbouring Zambia and Eswatini received 1,000 doses last month as part of a US programme, and were expected to launch the drug at World AIDS Day ceremonies.

Under the programme, manufacturer Gilead Sciences has agreed to provide lenacapavir at no profit to two million people in countries with a high HIV burden over three years.

Though the numbers of supplied has generated criticism, with Critics saying this is far below the actual requirement and that the market price is out of reach for most people.

Eastern and Southern Africa account for about 52 percent of the 40.8 million people living with HIV worldwide, according to 2024 UNAIDS data.

Generic versions of lenacapavir are expected to be available from 2027 at around $40 per year in more than 100 countries, through agreements by Unitaid and the Gates Foundation with Indian pharmaceutical companies.

Pre-exposure prophylaxis, or PrEP, has been used for over a decade to prevent HIV, but its reliance on a daily pill has limited its impact on global infections.